100000 - Document - Document and Entity Information
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995455 - Disclosure - Cybersecurity Risk Management, Strategy, and Governance
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995465 - Disclosure - Organization and Basis of Presentation
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995475 - Disclosure - Summary of Significant Accounting Policies
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995485 - Disclosure - Fair Value of Financial Assets and Liabilities
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995635 - Disclosure - Net Loss Per Share
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995665 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995755 - Disclosure - Warrants (Tables)
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995765 - Disclosure - Stock Options, Restricted Stock and Stock-Based Compensation (Tables)
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995845 - Disclosure - Fair Value of Financial Assets and Liabilities - Schedule of Information About Financial Assets and Liabilities Measured at Fair Value on Recurring Basis (Details)
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995855 - Disclosure - Fair Value of Financial Assets and Liabilities - Additional Information (Details)
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995865 - Disclosure - Fair Value of Financial Assets and Liabilities - Schedule of Aggregate Fair Values of Warrant Liabilities, for Which Fair Value Determined by Level 3 Inputs (Details)
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995875 - Disclosure - Fixed Assets, Net - Summary of Fixed Assets, Net (Details)
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995885 - Disclosure - Fixed Assets, Net - Additional Information (Details)
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995895 - Disclosure - Accrued Expenses - Schedule of Accrued Expenses (Details)
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995915 - Disclosure - Term Loan - Schedule of Principal Payments and Net Carrying Amount of Term Loan (Details)
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995925 - Disclosure - Borrowings under Paycheck Protection Program - Additional Information (Details)
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995935 - Disclosure - Other Long-Term Debt - Additional Information (Details)
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995945 - Disclosure - Lease - Additional Information (Details)
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995955 - Disclosure - Lease - Schedule of Other Information (Details)
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995965 - Disclosure - Lease - Summary of Future Lease Payments Under Non-cancellable Leases (Details)
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995975 - Disclosure - Lease - Summary of Future Minimum Lease Payments (Details)
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995985 - Disclosure - Common Stock - Additional Information (Details)
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995995 - Disclosure - Common Stock - Schedule of Common Stock Reserved For Future Issuance (Details)
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996005 - Disclosure - Warrants - Summary of Warrants Outstanding for Purchase of Common Stock (Details)
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996015 - Disclosure - Warrants - Additional Information (Details)
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996025 - Disclosure - Stock Options, Restricted Stock and Stock-Based Compensation - Additional Information (Details)
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996035 - Disclosure - Stock Options, Restricted Stock and Stock-Based Compensation - Schedule of Stock Option Activity (Details)
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996045 - Disclosure - Stock Options, Restricted Stock and Stock-Based Compensation - Schedule of Fair Value of Stock Options Granted Was Estimated on Black-Scholes Options (Details)
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996065 - Disclosure - Stock Options, Restricted Stock and Stock-Based Compensation - Schedule of Stock-based Compensation Expense (Details)
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996075 - Disclosure - Income Taxes - Additional Information (Details)
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996085 - Disclosure - Income Taxes - Schedule of Components of Income Tax Expense (Details)
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996095 - Disclosure - Income Taxes - Reconciliation of Effective Income Tax Rate (Details)
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996105 - Disclosure - Income Taxes - Schedule of Net Deferred Tax Assets (Details)
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996115 - Disclosure - Income Taxes - Summary of Changes in Valuation Allowance for Deferred Tax Assets (Details)
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996125 - Disclosure - Exclusive Licensing Agreement with a Related Party - Additional Information (Details)
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996135 - Disclosure - Exclusive Licensing Agreement with a Related Party - Additional Information (Details 1)
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996135 - Disclosure - Exclusive Licensing Agreement with a Related Party - Additional Information (Details 1) [Default]
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996145 - Disclosure - Technology License Agreement - Additional Information (Details)
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996155 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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996165 - Disclosure - Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share Attributable to Common Stockholders (Details)
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996175 - Disclosure - Net Loss Per Share - Schedule of Potential Shares of Common Stock Excluded from Computation of Diluted Net Loss Per Share (Details)
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996185 - Disclosure - Segment Reporting - Additional Information (Details)
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996195 - Disclosure - Segment Reporting - Summary of Disaggregated Amounts that Comprise Research and Development and General and Administrative Expenses (Details)
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996205 - Disclosure - Corporate Restructuring - Additional Information (Details)
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Statement [Line Items]
Statement [Line Items]
Capital Stock
Capital Stock [Text Block]
Capital stock.
Debt Instrument
Debt Instrument [Axis]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Plan Name
Plan Name [Domain]
Term loan.
Term Loan [Text Block]
Term Loan
Permanent adjustments
Effective Income Tax Rate Reconciliation Permanent Adjustments
Effective income tax rate reconciliation permanent adjustments.
Deferred revenue
Deferred Tax Assets, Deferred Income
Restricted stock unit vesting, net of shares withheld for taxes
Restricted stock unit vesting, net of shares withheld for taxes
Share-Based Payment Arrangement, Decrease for Tax Withholding Obligation
Summary of Warrants Outstanding for Purchase of Common Stock
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Summary of Changes in Valuation Allowance for Deferred Tax Assets
Summary of Valuation Allowance [Table Text Block]
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Revenue, remaining performance obligation, amount
Revenue, Remaining Performance Obligation, Amount
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Increase or decrease in percentage rate of Pre-funded warrants not in excess
Increase or decrease in percentage rate of Pre-funded warrants not in excess
Interest Paid, Excluding Capitalized Interest, Operating Activities
Cash paid for interest
Series B Conditional Warrants
Series B Conditional Warrants [Member]
Series B conditional warrants.
Unrecognized compensation cost related to unvested stock options
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Number of operating segment
Number of Operating Segments
Share-Based Payment Arrangement, Tranche One [Member]
Tranche One
Commercial purposes at a price of cost plus percentage
Commercial Purposes At Price Of Cost Plus Percentage
Commercial purposes at a price of cost plus percentage.
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Tax credits
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Exercisable as of December 31, 2024
Series C Preferred (As Converted To Common Stock)
Series C Preferred As Converted To Common Stock [Member]
Series C preferred as converted to common stock.
Schedule of other information related to operating leases.
Schedule of Other Information Related to Operating Leases [Table Text Block]
Schedule of Other Information
Class Of Warrant Or Right Period
Class of warrant or right period.
Class of warrant or right period
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested Options Forfeited, Weighted Average Grant Date Fair Value
Unvested as of December 31, 2024
Auditor Name
Federal
Deferred Federal Income Tax Expense (Benefit)
Temporary equity, shares issued
Temporary Equity, Shares Issued
Level 2
Fair Value, Inputs, Level 2 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Property and Equipment Estimated Useful Lives
Property Plant And Equipment Useful Lives Table [Text Block]
Property plant and equipment useful lives.
Long-Term Debt, Type [Domain]
Shares Available for Future Grant Under Stock Option Plan
Shares Available For Future Grant Under Stock Option Plan [Member]
Shares available for future grant under stock option plan.
Aggregate Intrinsic Value, Granted
Share Based Compensation Arrangement By Share Based Payment Award Options Granted Intrinsic Value
Share-based compensation arrangement by share-based payment award options granted intrinsic value.
Current portion of term loan payable to a bank
Less current portion
Long-Term Debt, Current Maturities
Long-Term Debt, Current Maturities, Total
Issuance of Common stock and Pre-funded Warrants in Public Offering, Net of Issuance Costs Value
Issuance of common stock and pre-funded warrants in public offering, net of issuance costs value.
Issuance of common stock and accompanying pre-funded warrants in public offering, net of issuance costs of $6.1 million
Income tax examination, description
Income Tax Examination, Description
Lessee, Operating Leases [Text Block]
Lease
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Restructuring Cost [Table]
Stock, Class of Stock [Table]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Schedule of Aggregate Fair Values of Warrant Liabilities, for Which Fair Value Determined by Level 3 Inputs
Loan Agreement
Loan Agreement [Member]
Loan agreement.
Loss related to indemnification obligations
Loss Contingency, Loss in Period
Investment, Name [Domain]
Technology License Agreement [Abstract]
Technology license agreement.
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Cybersecurity Risk Management Processes Integrated [Text Block]
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Interest expense
Equity [Text Block]
Common Stock
Facility And Equipment Costs
Facility and equipment costs.
Facility and equipment costs
Title of Individual
Title and Position [Axis]
Class of Warrant or Right
Class of Warrant or Right [Axis]
License Agreement [Abstract]
License agreement.
Sale of Stock
Sale of Stock [Domain]
Net carrying amount
Net carrying amount
Long-term debt
Principal
Entity Central Index Key
Entity Central Index Key
Warrants
Warrant [Member]
Fixed annual rate
Long-Term Debt, Percentage Bearing Fixed Interest, Percentage Rate
Auditor Opinion
Auditor Opinion [Text Block]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Table]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Stock issued during period under initial public offering
Common Stock, Shares, Issued, Total
Common stock, shares, issued
Common Stock, Shares, Issued
Other assets
Other Assets
Other Assets, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Risk-free interest rate, Minimum
IPO including Underwriters' Option
I P O Including Underwriters Overallotment Option [Member]
IPO including underwriters overallotment option.
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Increase (Decrease) in Prepaid Expense and Other Assets
Future payment made upon the achievement of sales
Future Payment Made Upon The Achievement Of Sales
Future payment made upon the achievement of sales.
Income Statement [Abstract]
General and Administrative Expense [Abstract]
General and administrative:
Entity Address, State or Province
Entity Address, State or Province
Class Of Warrant Or Right [Table]
Class of Warrant or Right [Table]
Deferred rent
Deferred Rent Credit, Noncurrent
Accounting Standards Update [Extensible Enumeration]
Office space noncancelable operating lease expiration date
Noncancelable Operating Lease Expiration Date
Noncancelable operating lease expiration date.
Pre-funded Warrants [Member]
Pre-funded Warrants.
Pre-funded Warrants
Pre-Funded Warrants
Non-cash interest expense
Non Cash Interest Expense
Non-cash interest expense.
Government Grants Policy [Text Block]
Government grants.
Government Grants
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Exercisable as of December 31, 2024
Liability Class
Liability Class [Axis]
Accretion of debt discount.
Accretion of debt discount
Accretion of debt discount
Issuance of Common stock and Pre-funded Warrants in Public Offering, Issuance Costs
Issuance of common stock and pre-funded warrants in public offering, issuance costs.
Issuance of common stock and accompanying pre-funded warrants in public offering, issuance costs
Class of warrant or right exercise average market price per share.
Class Of Warrant Or Right Exercise Average Market Price Per Share
Class of warrant or right exercise average market price per share
Cover
Cover [Abstract]
Cash and Cash Equivalents, Unrestricted Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Comprehensive income (loss)
Comprehensive Income, Policy [Policy Text Block]
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share - basic
Payment for outstanding note balance and accrued interest due
Payments to Acquire Notes Receivable
Cash proceeds amount equal to at least from the issuance and sale of equity securities
Cash proceeds Amount Equal to at least from the Issuance and Sale of Equity Securities
Cash proceeds Amount Equal to at least from the Issuance and Sale of Equity Securities.
Operating expenses:
Operating Expenses [Abstract]
Document Annual Report
Document Annual Report
Non-refundable fee
Non Refundable Fee
Non-refundable fee.
Asset Acquisition [Axis]
Total stock based compensation expense
Share-Based Payment Arrangement, Expense
Deferred tax assets lease liability.
Deferred Tax Assets Lease Liability
Lease liability
Long-term Debt, Total
Long-term debt
Long-Term Debt
Gross Proceeds Before Deducting Underwriting Discounts and Commissions and Other Offering Expenses
Gross Proceeds Before Deducting Underwriting Discounts and Commissions and Other Offering Expenses
Gross proceeds before deducting underwriting discounts and commissions, and offering expenses
Schedule of Common Stock Reserved For Future Issuance
Schedule Of Common Stock Reserved For Future Issuance Table [Text Block]
Schedule of common stock reserved for future issuance.
Deferred Tax Assets, Net [Abstract]
Deferred tax assets:
Nonvested Restricted Stock Shares Activity [Table Text Block]
Summary of Restricted Stock Activity
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit)
Plan Name
Plan Name [Axis]
Segment Reporting [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Stock Options, Shares Outstanding
Number of Stock Options, Shares Outstanding
Debt instrument final payment fee
Debt Instrument Final Payment Fee
Final payment fee
Class of warrant or right consecutive trading days 1.
Class Of Warrant Or Right Consecutive Trading Days 1
Number of consecutive days
Current assets:
Assets, Current [Abstract]
Common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Technology License Agreement [Line Items]
Technology License Agreement [Line Items]
Technology license agreement.
Temporary equity, Conversion of Series Preferred Stock to common stock
Conversion of Series Preferred Stock to common stock
Temporary Equity Stock Issued During Period Value Conversion of Convertible Securities
Temporary equity stock issued during period value conversion of convertible securities.
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Marketable debt securities maturities duration
Marketable Debt Securities Maturities Duration
Marketable debt securities maturities duration.
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted-Average Grant Date Fair Value, Forfeited
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Loan, maturity period
Debt Instrument, Term
Loan agreement period
Operating Loss Carryforwards, Total
Operating loss carryforwards
Operating Loss Carryforwards
Debt instrument subject to prepayment premium percentage
Debt Instrument Subject to Prepayment Premium Percentage
Debt instrument subject to prepayment premium percentage.
Fixed assets, net
Fixed assets, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net
2027
Lessee, Operating Lease, Liability, to be Paid, Year Four
2025
Cash Flows from Operating Activities:
Net Cash Provided by (Used in) Operating Activities [Abstract]
Type of Restructuring [Domain]
Fair Value, Recurring
Fair Value, Recurring [Member]
Current expense (benefit):
Current Income Tax Expense (Benefit), Continuing Operations [Abstract]
Restructuring and Related Activities [Abstract]
Schedule of Information About Financial Assets and Liabilities Measured at Fair Value on Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Vesting [Axis]
Extended expiration dates
Class Of Warrant Or Right Extended Expiration Dates
Class of warrant or right extended expiration dates.
Common stock par value
Common stock, par value
Common Stock, Par or Stated Value Per Share
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Recognition of unrealized loss on marketable securities
Unrealized gain on available-for-sale securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Temporary Equity Carrying Amount Attributable To Parent, Total
Convertible preferred stock
Temporary Equity, Beginning Balance
Temporary equity, Ending Balance
Temporary Equity, Carrying Amount, Attributable to Parent
Measurement Input Type
Measurement Input Type [Domain]
Statement of Cash Flows [Abstract]
Pre-clinical research
Pre-clinical research
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Outstanding Stock Options (As Converted To Common Stock)
Stock Options Outstanding
Stock Options Outstanding [Member]
Stock options outstanding.
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease), Total
Change in fair value
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Period Increase (Decrease)
SHARES OF COMMON STOCK SUBJECT TO WARRANTS
Class of warrants issued
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Intangibles
Deferred Tax Assets, Goodwill and Intangible Assets
Restructuring costs
Restructuring Costs
Restructuring Costs, Total
Minimum Beneficial Ownership Percentage
Minimum beneficial ownership percentage.
Minimum beneficial ownership percentage
Restricted Stock [Member]
Unvested Restricted Stock
Patent Costs Policy [Text Block]
Patent costs.
Patent Costs
Equity Components
Equity Components [Axis]
Entity Address, Address Line One
Entity Address, Address Line One
Schedule of Basic and Diluted Net Loss Per Share Attributable to Common Stockholders
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Technology License Agreement
Technology License Agreement [Text Block]
Technology license agreement.
Employee-related Liabilities, Current, Total
Payroll and employee related expenses
Employee-related Liabilities, Current
Employee Severance
Employee Severance [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of Shares Options, Granted
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Percentage income taxes benefits upon ultimate settlement
Percentage Income Taxes Benefits Upon Ultimate Settlement
Percentage income taxes benefits upon ultimate settlement.
Networking and Computer Equipment
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Research and Development Expense [Abstract]
Research and development:
Borrowings under Paycheck Protection Program
Subordinated Borrowings Disclosure [Text Block]
Subsequent Event Type [Axis]
Deferred expense (benefit):
Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract]
Total other income (expense), net
Nonoperating Income (Expense)
Schedule of Potential Shares of Common Stock Excluded from Computation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Loan, maximum borrowing capacity
Line of Credit Facility, Maximum Borrowing Capacity
Aggregate exercise price of common stock shares.
Aggregate Exercise Price Of Common Stock Shares
Common stock held by option holder in consideration of aggregate exercise price
Legal Entity of Counterparty, Type
Legal Entity of Counterparty, Type [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of Shares Options, Unvested
Number of Shares Options, Unvested
Entity Voluntary Filers
Entity Voluntary Filers
Amendment Flag
Amendment Flag
Accounting Standards Update 2016-02 [Member]
ASU 2016-02 (Topic 842)
Total current expense (benefit):
Current Income Tax Expense (Benefit)
Federal
Current Federal Tax Expense (Benefit)
Increase (Decrease) in Operating Lease Liability
Lease liability
Operating Lease, Liability, Noncurrent
Lease liability, net of current portion
EXPIRATION DATES
Expiration dates
Class of warrant or right expiration dates.
Warrants Expire date
Federal
Domestic Tax Jurisdiction [Member]
Debt Instrument, Name
Debt Instrument, Name [Domain]
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock
Sale of Stock, Price Per Share
Common stock, public offering price
Net loss
Net loss and comprehensive loss
Lessee, Lease, Description [Table]
Number of product candidates
Number Of Product Candidates
Number of product candidates.
Options exercised, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Stock options exercised
Number of Stock Options, Shares, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Exercisable as of December 31, 2024
Payment for license fee
Payment For License Fee
Payment for license fee.
Expected dividend assumed
Expected Dividend Assumed
Expected dividend assumed.
Variable Rate [Domain]
Research and Development
Research and Development Expense
Research and Development Expense [Member]
Schedule of Debt [Table Text Block]
Schedule of Principal Payments and Net Carrying Amount of Term Loan
Labor and Related Expense
Employee-related
Employee-related
Equity Component
Equity Component [Domain]
Statistical Measurement
Statistical Measurement [Domain]
Increases recorded to income tax provision
Deferred Tax Assets Valuation Allowance Increase Recorded To Income Tax Provision
Deferred tax assets valuation allowance increase recorded to income tax provision.
Document Financial Statement Error Correction [Flag]
General and administrative
General and Administrative Expense
Total general and administrative
Proceeds from the sale of fixed assets
Proceeds from Sale of Property, Plant, and Equipment
Proceeds from Sale of Property, Plant, and Equipment, Total
Interest Expense, Debt, Total
Interest Expense, Debt
Interest expense
State
Deferred State and Local Income Tax Expense (Benefit)
Share-based compensation arrangement by share-based payment award, expiration period
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Furniture and Fixtures
Furniture and Fixtures [Member]
Treasury Stock Member
Treasury Stock
Treasury Stock, Common [Member]
Cybersecurity Risk Management Processes Integrated [Flag]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]
Preferred Stock, Shares Issued, Total
Preferred stock, shares issued
Preferred Stock, Shares Issued
Operating cash flows used for operating leases
Operating Lease, Payments
Cash paid for amounts included in measurement of lease liability
Proceeds from option exercises
Proceeds from Stock Options Exercised
Debt Instrument, Unamortized Discount, Total
Debt Instrument, Unamortized Discount
Less: debt discount
Share-based Compensation Number of Shares
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Unvested as of December 31, 2024
Payables and Accruals [Abstract]
Maximum amount upon achievement of various clinical, commercial and sales milestones
Maximum Amount Upon Achievement Of Various Clinical Commercial And Sales Milestones
Maximum amount upon achievement of various clinical, commercial and sales milestones.
Deferred Tax Liabilities, Other
Other
Operating Lease, Expense
Rent expense
Exclusive Licensing Agreement
Exclusive Licensing Agreement [Member]
Exclusive licensing agreement.
Deferred Revenue, Noncurrent, Total
Deferred revenue
Deferred Revenue, Noncurrent
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Risk-free interest rate, Maximum
Number of consecutive
Number of Consecutive Installments
Number of consecutive installments.
Restricted Cash, Noncurrent
Restricted cash
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Class of Stock
Class of Stock [Domain]
Severance cost
Severance Costs
Exclusive Licensing Agreement with a Related Party
Collaborative Arrangement Disclosure [Text Block]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Common stock, shares, outstanding
Beginning Balance, Shares
Ending Balance, Shares
Common Stock, Shares, Outstanding
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Warrants
Warrants Disclosure [Text Block]
Warrants disclosure.
Preferred stock par value
Preferred Stock, Par or Stated Value Per Share
Temporary equity, Conversion of Series Preferred Stock to common stock, Shares
Conversion of Series Preferred Stock to common stock, Shares
Temporary Equity Stock Issued During Period Shares Conversion of Convertible Securities
Temporary equity stock issued during period shares conversion of convertible securities.
Deferred Tax Assets Capitalized Research And Development Expenditures
Deferred Tax Assets Capitalized Research And Development Expenditures
Capitalized R&D expenditures
Sale of common stock through at-the-market offerings, issuance costs
Sale of common stock through at-the-market offerings, issuance costs
Antidilutive Securities
Antidilutive Securities [Axis]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
Entity Interactive Data Current
Entity Interactive Data Current
Lease expiration date
Lease Expiration Date
Legal Entity Type of Counterparty
Legal Entity Type of Counterparty [Domain]
Accounting Standards Update
Accounting Standards Update [Domain]
Significant Accounting Policies [Table]
Significant Accounting Policies [Table]
Significant accounting policies.
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted-Average Grant Date Fair Value, Vested
Related Party Transaction
Related Party Transaction [Domain]
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, cash equivalents and restricted cash at beginning of period
Cash, cash equivalents and restricted cash at end of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Statistical Measurement
Statistical Measurement [Axis]
Operating Lease, Cost
Operating lease cost
Share-Based Payment Arrangement, Tranche Three [Member]
Tranche Three
Significant Accounting Policies [Line Items]
Significant Accounting Policies [Line Items]
Significant accounting policies.
Related Party
Related and Nonrelated Parties [Domain]
Lease, Cost, Total
Lease, Cost
Total lease expense
Summary of Future Minimum Lease Payments
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Summary of Future Lease Payments Under Non-cancelable Leases
Income Taxes [Line Items]
Income Taxes [Line Items]
Income Taxes.
Deferred tax liabilities right of use asset.
Deferred Tax Liabilities Right Of Use Asset
Right of use asset
Number of shares available for grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-Average Grant Date Fair Value, Granted
Stock-based awards are expected to be recognized over a weighted average period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Interest income
Interest and Other Income
Deferred Tax Assets, Net
Net deferred tax assets (liabilities)
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs and Accruals
Thereafter
Lessee Operating Lease Liability To Be Paid After Year Four
Lessee operating lease liability to be paid after year four.
Income Statement Location
Statement of Income Location, Balance [Axis]
Committed period to remitting in support of clinical trial
Committed Period To Remitting In Support Of Clinical Trial
Committed period to remitting in support of clinical trial.
Total assets
Assets
Expected option life (years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Restructuring Type [Axis]
Debt Instrument [Table]
Schedule of Long-Term Debt Instruments [Table]
Conditional series B warrants member.
Conditional Series B Warrants [Member]
Conditional Series B Warrants
Deferred Tax Liabilities, Gross, Total
Deferred Tax Liabilities, Gross
Total deferred tax liabilities
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of Shares Options, Vested
Promissory note contractual interest rate
Promissory Note Contractual Interest Rate
Promissory note contractual interest rate.
Promissory Note
Promissory Note [Member]
Promissory note.
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted and Issued Accounting Standards
Entity Address, City or Town
Entity Address, City or Town
Accumulated Other Comprehensive Loss
AOCI Attributable to Parent [Member]
Equity [Abstract]
Auditor Location
Payments of Stock Issuance Costs
Common stock and accompanying pre-funded warrants in public offering issuance costs
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of Shares Options, Forfeited
Combination of common stock, preferred stock, debt securities, warrants and units.
Combination of Common Stock, Preferred Stock, Debt Securities, Warrants and Units [Member]
Combination of Common Stock, Preferred Stock, Debt Securities, Warrants and/or Units
Payment related to restructuring plan
Payments for Restructuring
Other Long-Term Debt, Noncurrent
Other long-term debt
Fair value of warrant liability
Warrant liability
Warrant Liability Noncurrent
Warrant liability noncurrent.
Seshu Tyagarajan [Member]
Seshu tyagarajan.
Total principal
Debt Instrument, Face Amount
Business acquisition carrying value of promissory note.
Business Acquisition Carrying Value Of Promissory Note
Business acquisition carrying value of note
Restructuring Cost and Reserve [Line Items]
Accounting Standards Update 2020-06 [Member]
ASU 2020-06
Depreciation expense
Depreciation
Depreciation, Total
Numerator:
Net Income (Loss) Attributable to Parent [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Aggregate fair value of awards that vested
Debt instrument final payment fee percentage
Debt Instrument Final Payment Fee Percentage
Debt instrument final payment fee percentage.
Schedule of Segment Reporting Information, by Segment [Table]
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
BWH License
Brigham And Womens Hospital Inc License Agreement [Member]
Brigham and Womens Hospital, Inc License Agreement.
Loan forgiveness
Debt Instrument, Decrease, Forgiveness
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
Equity compensation
Share-Based Payment Arrangement [Text Block]
Stock Options, Restricted Stock and Stock-Based Compensation
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Construction in Progress
Construction in Progress [Member]
Weighted- Average Remaining Contractual Term (In Years), Granted
Share-based Compensation Arrangement by Share-based Payment Award Options Grants in Period Weighted Average Remaining Contractual Term
Share-based compensation arrangement by share-based payment award options grants in period weighted average remaining contractual term.
State
Current State and Local Tax Expense (Benefit)
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Segment Reporting, CODM, Individual Title and Position or Group Name
Fair Value Disclosures [Abstract]
Proceeds from Principal payments on term loan
Principal payments on term loan
Principal payments on term loan
Entity Public Float
Entity Public Float
Weighted-Average Exercise Price, Cancelled, forfeited or expired
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Ventagen
Ventagen L L C [Member]
Ventagen, LLC.
Asset acquisition, assumption of promissory note
Asset Acquisition Assumption of Promissory Note
Asset acquisition, assumption of promissory note.
Proceeds from IPO, net
Stock Issued During Period, Value, New Issues
Sale of stock under Shelf
Sale of common stock through at-the-market offerings, net of issuance costs of $0.5 million
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]
Summary of Future Minimum Lease Payments Under Facility Lease
Net deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Options exercised
Stock Issued During Period, Value, Stock Options Exercised
Lessee, Lease, Description [Line Items]
Current liabilities:
Liabilities, Current [Abstract]
Document Type
Document Type
Accounting Standards Update
Accounting Standards Update [Axis]
Title of 12(b) Security
Title of 12(b) Security
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value
Statement of Stockholders' Equity [Abstract]
Balance
Balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Document Fiscal Period Focus
Document Fiscal Period Focus
Payment at the time of entering into license
Payment At Time Of Entering Into License
Payment at the time of entering into license.
Acquired assets represent in-process research and development
Research and development
Research and Development Expense
Total research and development
Payments related to tax withholding for vested restricted stock units
Payments related to tax withholding for vested restricted stock units
Payment, Tax Withholding, Share-Based Payment Arrangement
Long-term portion
Long-Term Debt, Excluding Current Maturities
Long-Term Debt, Excluding Current Maturities, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of Stock Options, Shares, Granted
Massachusetts
MASSACHUSETTS
Total fixed assets
Property, Plant and Equipment, Gross, Total
Construction in progress
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross
Consolidation, Policy [Policy Text Block]
Principles of Consolidation
Subsequent Event Type [Domain]
Leases
Lessee, Leases [Policy Text Block]
Schedule of Fair Value of Stock Options Granted Was Estimated on Black-Scholes Options
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Warrants exercised, Shares
Stock Issued During Period Shares Warrant Exercised
Stock issued during period shares warrant exercised.
Class of warrants shares exercised
Technology License Agreement [Table]
Technology License Agreement [Table]
Technology license agreement.
EXERCISE PRICE PER SHARE
Class of warrants issued per share
Exercise price per share
Francesca Barone [Member]
Francesca barone .
Revenue, remaining performance obligation, expected timing of satisfaction, period
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period
Class Of Warrant Or Right [Line Items]
Class of Warrant or Right [Line Items]
Sale of Stock
Sale of Stock [Axis]
Cash Flows from Investing Activities:
Net Cash Provided by (Used in) Investing Activities [Abstract]
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Research and development service revenue, related party
Revenue from Contract with Customer, Excluding Assessed Tax
Income Taxes
Income Tax Disclosure [Text Block]
Reconciliation of Effective Income Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Warrants and Rights Note Disclosure [Abstract]
Accrued expenses & other
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Other
Debt instrument, payment
Debt Instrument, Frequency of Periodic Payment
Other Accrued Liabilities, Current
Other
Increase (Decrease) in Accounts Payable, Total
Accounts payable
Increase (Decrease) in Accounts Payable
Deferred Tax Liabilities, Net [Abstract]
Deferred tax liabilities:
Entity Address, Address Line Two
Entity Address, Address Line Two
Impairment long lived asset held for use statement of income or comprehensive income extensible enumeration not disclosed flag
Impairment Long Lived Asset Held For Use Statement Of Income Or Comprehensive Income Extensible Enumeration Not Disclosed Flag
Impairment long lived asset held for use statement of income or comprehensive income extensible enumeration not disclosed flag.
Liabilities, Convertible Preferred Stock and Stockholders’ Deficit
Liabilities and Equity [Abstract]
Upfront license fee
Upfront License Fee
Upfront license fee.
Document Period End Date
Document Period End Date
Net Cash Provided by (Used in) Financing Activities
Net cash provided by (used in) financing activities
Impairment of fixed assets
Tangible Asset Impairment Charges
Tangible Asset Impairment Charges, Total
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Effective income tax rate
Effective Income Tax Rate Reconciliation, Percent
Anti-dilutive securities excluded from computation of earnings per share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Charles Schoch [Member]
Charles schoch.
Series B Preferred (As Converted To Common Stock)
Series B Preferred As Converted To Common Stock [Member]
Series B preferred as converted to common stock.
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Related party transactions, ownership percentage
Equity Method Investment, Ownership Percentage
Sale of Stock, Consideration Received on Transaction
Proceeds from stock offering
Accrued expenses
Accrued expenses
Accrued Liabilities, Current
Other Research and Development Expense
Other research and development segment expenses
Mark to market
Effective Income Tax Rate Reconciliation Mark to Market
Effective income tax rate reconciliation mark to market.
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Total income tax expense (benefit):
Income Tax Expense (Benefit)
Income tax expense (benefit)
Long-term debt, measurement input
Long-Term Debt, Measurement Input
Trading Symbol
Trading Symbol
Variable Rate [Axis]
Total stockholders' equity
Beginning Balance
Ending Balance
Equity, Attributable to Parent
2021 Plan
Two Thousand Twenty One Equity Incentive Plan [Member]
2021 Equity incentive plan.
Total deferred tax assets
Deferred Tax Assets, Gross
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Class of Warrant or Right, Outstanding
Number of warrants outstanding
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units
Unvested Restricted Stock
Sale of Stock, Number of Shares Issued in Transaction
Additional sales
Temporary equity, shares authorized
Temporary Equity, Shares Authorized
Variable Lease, Cost
Variable lease cost
Schedule Of Property Plant And Equipment [Table]
Property, Plant and Equipment [Table]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Emerging Growth Company Policy [Text Block]
Emerging growth company.
Emerging Growth Company
Unsecured Debt, Total
Unsecured loan
Unsecured Debt
Debt, Weighted Average Interest Rate
Weighted average effective interest rate
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Schedule of Stock-based Compensation Expense
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Measurement Input Type
Measurement Input Type [Axis]
Total deferred expense (benefit):
Deferred Income Tax Expense (Benefit)
Geographical
Geographical [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Intrinsic value of stock options exercised
Leases [Abstract]
Laboratory Equipment
Equipment [Member]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Conversion of Series Preferred Stock to common stock
Stock Issued During Period, Value, Conversion of Convertible Securities
Related Party
Related Party [Member]
Capital Stock [Abstract]
Capital stock.
Debt instrument, credit rating
Debt Instrument, Credit Rating
Class of Stock [Line Items]
Loan agreement date
Line of Credit Facility, Initiation Date
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Expected volatility, Minimum
Operating loss carryforwards subject to expiration
Operating Loss Carryforwards, Subject to Expiration
Operating loss carryforwards, subject to expiration.
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Security Exchange Name
Security Exchange Name
Fair Value by Liability Class
Fair Value by Liability Class [Domain]
Deferred Tax Assets, Tax Credit Carryforwards, Total
Credits
Deferred Tax Assets, Tax Credit Carryforwards
Total operating expenses
Operating Expenses
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Class of Stock
Class of Stock [Axis]
Change in fair value of NC Ohio Trust Warrants
Adjustments to Additional Paid in Capital, Fair Value
Less accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Fair Value Disclosures [Text Block]
Fair Value of Financial Assets and Liabilities
2026
Lessee, Operating Lease, Liability, to be Paid, Year Three
2024
Term Loan
Term Loan [Member]
Term loan.
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Subsequent Event
Subsequent Event [Member]
Maximum
Maximum
Maximum [Member]
Corporate Restructuring
Restructuring and Related Activities Disclosure [Text Block]
Total liabilities and stockholders' equity
Liabilities and Equity
Percentage of reduction in workforce positions
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Operating Lease, Right-of-Use Asset
Lease right of use assets
Supplemental cash flow information:
Supplemental Cash Flow Information [Abstract]
Total
Financial Liabilities Fair Value Disclosure
Series B Warrants
Series B Warrants [Member]
Series B warrants.
Prime Rate
Prime Rate [Member]
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share - diluted
Leasehold Improvements
Leasehold Improvements [Member]
Estimated market rate for unsecured loan
Estimated Market Rate For Unsecured Loan
Estimated market rate for unsecured loan.
Entity Ex Transition Period
Entity Ex Transition Period
Total liabilities
Liabilities
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Total current assets
Assets, Current
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Shares of common stock sold and issued
Stock Issued During Period, Shares, New Issues
Sale of common stock through at-the-market offerings, net of issuance costs of 05. million, Shares
Valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Share-based compensation arrangement by share-based payment award, award vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Entity Filer Category
Entity Filer Category
Property, Plant and Equipment [Abstract]
Asset Acquisition [Domain]
Organization and Basis of Presentation
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Other income (expense):
Nonoperating Income (Expense) [Abstract]
Current Fiscal Year End Date
Current Fiscal Year End Date
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: imputed interest
Organization And Basis Of Presentation [Line Items]
Organization And Basis Of Presentation [Line Items]
Organization and basis of presentation.
Series B Warrant Liability
Series B Warrant Liability [Member]
Series B warrant liability.
Temporary equity, par value
Temporary Equity, Par or Stated Value Per Share
Share-based Payment Arrangement, Noncash Expense, Total
Non-cash stock compensation expense
Share-Based Payment Arrangement, Noncash Expense
Expense for startup and patient fees for clinical trials
Expense For Startup And Patient Fees For Clinical Trials
Expense for startup and patient fees for clinical trials.
Related Party Transaction
Related Party Transaction [Axis]
Aggregate Intrinsic Value, Outstanding
Aggregate Intrinsic Value, Outstanding
Aggregate Intrinsic Value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Related Party
Related and Nonrelated Parties [Axis]
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]
Entity Registrant Name
Entity Registrant Name
Earning per share basic and diluted.
Earning Per Share Basic and Diluted [Abstract]
Denominator:
Change in Accounting Principle, Accounting Standards Update, Early Adoption [true false]
Change in Accounting Principle, Accounting Standards Update, Early Adoption [true false]
Related party costs
Cost of Revenue
Cost of Revenue, Total
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Earnings Per Share [Text Block]
Net Loss Per Share
Debt Instrument, Maturity Date
Debt instrument, maturity date
Entity Emerging Growth Company
Entity Emerging Growth Company
Public Offering [Member]
Public Offering [Member]
December 2024 Public Offering
Public Offering
Income Taxes [Table]
Income Taxes [Table]
Income Taxes.
Other Liabilities, Current, Total
Other current liabilities
Other Liabilities, Current
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted-average common shares outstanding, basic
Weighted-average shares of common stock outstanding - basic
Vesting [Domain]
Reduction in workforce positions
Restructuring and Related Cost, Number of Positions Eliminated
Estimated fair value of warrants
Warrants Not Settleable in Cash, Fair Value Disclosure
Tax credit carryforward, begin to expire year
Tax Credit Carryforward Expiration Start Year
Tax credit carryforward expiration start year.
Series A warrants.
Series A Warrants [Member]
Series A Warrants
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Expected volatility, Maximum
Common stock, shares authorized
Common Stock, Shares Authorized
Restricted stock unit vesting, net of shares withheld for taxes, Shares
Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation
Estimated Useful Life
Property, Plant and Equipment, Useful Life
Outstanding Warrants For Common Stock
Outstanding Warrants For Common Stock [Member]
Outstanding warrants for common stock.
Proceeds from Issuance of Common Stock
Proceeds from sale of common stock through at-the-market offerings, net of issuance costs
Net proceeds
Level 1
Fair Value, Inputs, Level 1 [Member]
Paycheck Protection Program, CARES Act
Paycheck Protection Program C A R E S Act [Member]
Paycheck Protection Program, CARES Act.
Employee Related Research and Development
Employee related research and development.
Employee-related
Debt Disclosure [Abstract]
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Weighted-Average Exercise Price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted- Average Remaining Contractual Term (In Years), Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Earnings Per Share, Policy [Policy Text Block]
Net Loss Per Share
General and Administrative
General and Administrative Expense
General and Administrative Expense [Member]
Long-lived assets, impairment charge
Impairment, Long-Lived Asset, Held-for-Use, Total
Long-lived assets, impairment charge
Impairment, Long-Lived Asset, Held-for-Use
W. Garrett Nichols [Member]
W. Garrett nichols.
Share-Based Payment Arrangement [Abstract]
Non Rule 10b51 Arr Modified Flag.
Non Rule 10b51 Arr Modified Flag
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-lived Assets
Warrant Liability Current
Warrant liability current.
Warrant liability
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Long-term debt, due month and year
Long Term Debt Due Month And Year
Long term debt due month and year.
Cybersecurity Risk Role of Management [Text Block]
Accounting Policies [Abstract]
Change In Beneficial Ownership Notice Period
Change in beneficial ownership notice period.
Change in beneficial ownership notice period
Schedule of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Public float issuing securities
Public Float Issuing Securities
Public Float Issuing Securities
Income Tax Disclosure [Abstract]
Stockholders' equity
Equity, Attributable to Parent [Abstract]
Periphagen, Inc.
Periphagen Inc Asset Acquisition [Member]
Periphagen, Inc. asset acquisition.
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Statement [Table]
Statement [Table]
Segment Information
Segment Reporting, Policy [Policy Text Block]
Summary of Fixed Assets, Net
Property, Plant and Equipment [Table Text Block]
Debt instrument accretion of debt discount.
Debt Instrument Accretion of Debt Discount
Accretion of debt discount
Past services provided by beneficiary
Past Services Provided By Beneficiary
Past services provided by beneficiary.
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
At-the-market offering.
At-the-Market Offering [Member]
ATM Program
At-the-Market Offerings
Change in fair value of warrant liability
Change in fair value of warrant liability
Fair Value Adjustment of Warrants
Entity File Number
Entity File Number
Segment Reporting Disclosure [Text Block]
Segment Reporting
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net increase (decrease) in cash, cash equivalents and restricted cash
Earnings Per Share [Abstract]
2015 Plan
Two Thousand Fifteen Stock Plan [Member]
2015 Stock Plan.
Stock compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
State taxes, net of federal benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Class of warrant or right exercise price per share.
Class Of Warrant Or Right Exercise Price Per Share
Class of warrant or right exercise price per share
Due from related parties
Other Receivables
Statement of Financial Position [Abstract]
Interest Expense, Operating and Nonoperating
Interest Expense, Operating and Nonoperating, Total
Interest expense
IPO
IPO [Member]
Loss from operations
Operating Income (Loss)
Loss from operations
Long-Term Debt, Maturity, Year One
2025
Shares Issued, Price Per Share
Public offering price
Entity Shell Company
Entity Shell Company
Accrued Professional Fees, Current
Professional fees
Entity Tax Identification Number
Entity Tax Identification Number
Assets
Assets [Abstract]
Proceeds from Issuance of Common Stock and Pre-funded Warrants
Proceeds from issuance of common stock and pre-funded warrants.
Proceeds from issuance of common stock and accompanying pre-funded warrants in public offering, net of issuance costs
Class of Warrant or Right
Class of Warrant or Right [Domain]
Govenment
Government [Member]
Payment from related party
Related Party Transaction, Amounts of Transaction
Series C Convertible Preferred Stock
Series C Convertible Preferred Stock [Member]
Series C convertible preferred stock.
Entity Current Reporting Status
Entity Current Reporting Status
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Exercisable as of December 31, 2024
Business Development
Clinical development
Business acquisition present value of future cash outflow
Business Acquisition Present Value Of Future Cash Outflow
Business acquisition present value of the future cash outflow.
Property, Plant and Equipment Disclosure [Text Block]
Fixed Assets, Net
Long-Term Debt, Type [Axis]
Revenue from Contract with Customer [Policy Text Block]
Revenue Recognition
Increase (Decrease) in Contract with Customer, Liability
Deferred income
Geographical
Geographical [Domain]
Document Fiscal Year Focus
Document Fiscal Year Focus
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Other General and Administrative Expense
Other general and administrative segment expenses
Share-Based Payment Arrangement, Tranche Two [Member]
Tranche Two
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued
Preferred stock, $0.01 par value; 10,000,000 shares authorized at December 31, 2024 and 2023; no shares issued or outstanding at December 31, 2024 and 2023, respectively.
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period
Number of Stock Options, Shares, Cancelled, forfeited or expired
Paul Peter Tak [Member]
Paul peter tak.
Tax credit carryforward
Tax Credit Carryforward, Amount
City Area Code
City Area Code
Non-cash lease expense.
Non-cash lease expense
Non-cash lease expense
Total current liabilities
Liabilities, Current
Income at US statutory rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Conversion of Series Preferred Stock to common stock, Shares
Stock Issued During Period, Shares, Conversion of Convertible Securities
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Local Phone Number
Local Phone Number
Series B Convertible Preferred Stock
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock.
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Income Tax Authority
Income Tax Jurisdiction [Axis]
Income Tax, Policy [Policy Text Block]
Income Taxes
Commitments and Contingencies Disclosure [Abstract]
Treasury Stock, Value, Total
Treasury Stock, Value
Treasury stock (at cost)
Treasury stock (at cost)
Liabilities:
Financial Liabilities Fair Value Disclosure [Abstract]
Committed amount to remitting in support of clinical trial
Committed Amount To Remitting In Support Of Clinical Trial
Committed amount to remitting in support of clinical trial.
Debt Issuance Costs, Net, Total
Debt Issuance Costs, Net
Debt issuance costs
Schedule of Net Deferred Tax Assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Professional Fees
Professional and consulting fees
Operating Lease, Liability, Current
Current portion of lease liability
Income Tax Authority
Income Tax Jurisdiction [Domain]
Operating loss carryforwards, begin to expire year
Operating Loss Carryforwards Expiration Start Year
Operating loss carryforwards expiration start year.
Accumulated Deficit
Retained Earnings [Member]
Underwriters’ Overallotment Option
Over-Allotment Option [Member]
Accrued interest due upon maturity period
Accrued Interest Due Upon Maturity Period
Accrued interest due upon maturity period.
Purchase of fixed assets
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Sharebased Compensation Arrangement By Sharebased Payment Award Option Unvested Weighted Average Remaining Contractual
Share based compensation arrangement by share based payment award option unvested weighted average remaining contractual.
Unvested as of December 31, 2024
Document Transition Report
Document Transition Report
Debt instrument, commencing date
Debt Instrument, Date of First Required Payment
Other assets
Increase (Decrease) in Other Operating Assets
Increase (Decrease) in Other Operating Assets, Total
Lessee, Operating Lease, Liability, to be Paid, Year Two
2023
2026
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Weighted-Average Exercise Price, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Laboratory Equipment
Laboratory Equipment [Member]
Laboratory equipment.
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Area of lease property
Area Of Lease Property
Area of lease property.
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentrations of Credit Risk
Auditor Firm ID
Minimum
Minimum
Minimum [Member]
Common Stock
Common Stock [Member]
Restricted Cash, Total
Restricted cash
Restricted Cash
Long-Term Debt, Maturity, Year Two
2026
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses
Rule 10b51 Arr Modified Flag.
Rule 10b51 Arr Modified Flag
Investment, Name [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted-Average Grant Date Fair Value, Unvested
Weighted-Average Grant Date Fair Value, Unvested
Additional Paid In Capital
Additional Paid-in Capital [Member]
Restricted stock unit vesting, Shares
Stock Issued During Period Shares Restricted Stock Unit Vesting
Stock issued during period shares restricted stock unit vesting.
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Other comprehensive gain:
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Income Statement Location
Statement of Income Location, Balance [Domain]
Lessee, Operating Lease, Liability, to be Paid, Year One
2022
2025
Decreases recorded to income tax provision
Increases recorded to income tax provision
Deferred Tax Assets Valuation Allowance Decrease Recorded To Income Tax Provision
Deferred tax assets valuation allowance decrease recorded to income tax provision.
Payment for annual license fee
Payment For Annual License Fee
Payment for annual license fee.
Acquisition
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Purchases
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Measurement Input, Credit Rate
Measurement Input Credit Rate [Member]
Measurement input credit rate.
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Title of Individual
Title and Position [Domain]
Warrant liability
Warrants and Rights Outstanding
Pre-funded warrants issued and sold to purchase shares
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued
Common stock, $0.01 par value; 150,000,000 shares authorized at December 31, 2024 and 2023; 46,933,088 and 29,213,627 shares issued at December 31, 2024 and 2023, respectively; and 46,810,480 and 29,091,019 shares outstanding at December 31, 2024 and 2023, respectively.
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Founders
Executive Officer [Member]
Unpaid severance costs
Unpaid Severance Costs1
Unpaid severance costs.
Loss on the sale of fixed assets
Loss on the sale of fixed assets
Gain (Loss) on Disposition of Assets
Gain (Loss) on Disposition of Assets, Total
Impairment, Long-Lived Asset, Held-for-Use, Statement of Income or Comprehensive Income [Extensible Enumeration]
Share based compensation award tranche four member.
Share Based Compensation Award Tranche Four [Member]
Tranche Four
Corporate, Clinical and Manufacturing Operations
Corporate Clinical And Manufacturing Operations [Member]
Corporate clinical and manufacturing operations.
2026
Long-Term Debt, Maturity, Year Three
Operating Lease, Liability
Total lease liability
Operating lease liability
Lease liability
Loans Payable to Bank, Noncurrent
Net carrying amount
Term loan payable to a bank
Voting stock.
Voting Stock [Member]
Voting Stock
Measurement Frequency
Measurement Frequency [Axis]
Schedule of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating losses
Deferred Tax Assets, Operating Loss Carryforwards
Commitments and contingencies (Note 15)
Commitments and Contingencies
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted-average common shares outstanding, diluted
Weighted-average shares of common stock outstanding - diluted
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Summary of Disaggregated Amounts that Comprise Research and Development and General and Administrative Expenses
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Lessee, Operating Lease, Liability, to be Paid
Total future lease payments
Cybersecurity Risk Management Third Party Engaged [Flag]
Share-based Compensation Arrangement by Share-based Payment Award Options Non-vested Intrinsic Value
Share-based compensation arrangement by share-based payment award options non-vested intrinsic value.
Unvested as of December 31, 2024
Nonoperating Gains (Losses), Total
Grant income
Nonoperating Gains (Losses)
Grant revenue
Class of warrant or right issued
Class Of Warrant Or Right Issued
Class of warrant or right issued.
Entity Small Business
Entity Small Business
Segment Reporting Information [Line Items]
Third-party research and development expenses
Accrued Third Party Research And Development Expenses Current
Accrued third-party research and development expenses current.
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Interest rate
Debt Instrument, Basis Spread on Variable Rate
Debt Disclosure [Text Block]
Other Long-Term Debt
Cash and cash equivalent maturity period
Cash And Cash Equivalent Maturity Period
Cash and cash equivalent maturity period.
Operating Leases, Rent Expense
Rent expense
Line of Credit Facility [Abstract]
Organization And Basis Of Presentation [Table]
Organization And Basis Of Presentation [Table]
Organization and basis of presentation.
Issuance of Common stock and Pre-funded Warrants in Public Offering, Net of Issuance Costs, Shares
Issuance of common stock and pre-funded warrants in public offering, net of issuance costs, Shares
Issuance of common stock and accompanying pre-funded warrants in public offering, net of issuance costs of $6.1million, Shares
Manufacturing Equipment
Manufacturing Equipment [Member]
Manufacturing equipment
Cash Flows from Financing Activities:
Net Cash Provided by (Used in) Financing Activities [Abstract]
Weighted-Average Exercise Price, Outstanding
Weighted-Average Exercise Price, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Restricted stock unit vesting
Stock Issued During Period Value Restricted Stock Unit Vesting
Stock issued during period value restricted stock unit vesting.
Weighted-average incremental borrowing rate.
Weighted-average Incremental Borrowing Rate
Weighted-average incremental borrowing rate
Unsecured Note
Unsecured Debt [Member]
State
State and Local Jurisdiction [Member]
Measurement Frequency
Measurement Frequency [Domain]
Operating loss carryforwards indefinite
Operating Loss Carryforwards Indefinite
Operating loss carryforwards indefinite.
Valuation allowance
Deferred Tax Assets, Valuation Allowance, Total
Valuation allowance
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Temporary equity, shares outstanding
Temporary Equity, Beginning Balance, Shares
Temporary equity, Ending Balance, Shares
Temporary Equity, Shares Outstanding
Level 3
Fair Value, Inputs, Level 3 [Member]
Operating Lease, Weighted Average Remaining Lease Term
Weighted-average remaining lease term (years)
NC Ohio Trust
N C Ohio Trust Warrants [Member]
NC Ohio trust warrants.
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Accounting standards update 2020 05.
Accounting Standards Update 2020 05 [Member]
ASU 2020-05
Increase (Decrease) in Accrued Liabilities, Total
Accrued expenses
Increase (Decrease) in Accrued Liabilities